Extravasation: Definition, symptoms, and treatment

iv drug use complications

The same study revealed the readmission rate within one year for the combined diagnoses (DVT or PE) was 5.3% for primary and 14.3% for secondary diagnoses [143]. Another theory explains this association of IV drug use and DVT to be due to the citric acid used to dissolve these drugs. Most heroin available reaches a pH of nearly 4, which is quite low as compared to the normal pH within blood vessels [6,33-34,42]. Prescription pain relievers were misused by 9.7 million people in the United States by 2019. Despite a decrease from the peak observed in 2011, and from overall opioid use statistics of consumption that were particularly high from 2002 to 2018, these numbers remain high. In 2019, there was a decrease in opioid use across all age groups, particularly among adolescents [26].

Infectious Diseases in Persons Who Inject Drugs

  • I’ve taken care of patients who have been in their 20s and have lost feet and hands because of complications from IV drug use.
  • Intravenous drug abusers with DVT have poor outcomes with high morbidity, mortality, and healthcare costs as compared to the general population.
  • Patients with a habit of injection drug use must be educated about venous problems, and access to proper medical treatment must be made easier [45,110].
  • There are over 50 conditions that present with swollen and painful limbs comparable to DVT in IVDU, making precise diagnosis critical for timely treatment.
  • On CT, abscesses appear as a well-defined collection with internal fluid density and a peripheral rim-enhancing pseudocapsule (Fig. ​(Fig.3)3) [8].
  • Illicit drug use carries with it social stigma, and patients may be reluctant to admit to using, so it is important to look for and recognize the clinical manifestations of drug use.

Without adequate blood flow, the injury is unable to heal properly and can turn into an ulcer. When a virus, bacteria or other germs are introduced and trapped beneath the skin, an abscess can form. Local infection in the skin results in the body’s immune system trying to defend itself from the infection by sending white blood cells to the infected area. The immune system causes swelling to develop, and pus is created from the combination of white blood cells, germs and damaged tissues.

iv drug use complications

Septic Arthritis

A psoas abscess is a recognised complication of injection into the ipsilateral groin, for example. Social-ecological models with respect to drug-related risk and harms emphasize the complex interplay between both behavioral and structural factors, with the need for a multi-level approach to harm reduction [31, 32]. Infectious complications are the most common reason for inpatient admission iv drug use in PWID [7]. Soft tissue infection due to intravenous injection with contaminated needles or subcutaneous/intramuscular injection may manifest as a range of disorders of varying severity which include cellulitis, abscess, myositis and necrotising fasciitis. These infections are often polymicrobial and Staphylococcus aureus and Streptococcus pyogenes are among the most common organisms [7].

  • This complication arises when a non-vesicant drug seeps out of the vein into nearby tissue.
  • Talk with your health care provider or see a mental health provider, such as a doctor who specializes in addiction medicine or addiction psychiatry, or a licensed alcohol and drug counselor.
  • Physical examination revealed nasal purulence, allodynia over the right side of the face without overlying erythema, and oropharyngeal exudate.
  • The addicting drug causes physical changes to some nerve cells (neurons) in your brain.

Assistance for persons who use drugs

iv drug use complications

The lack of a notable difference between hospital readmission rates between the two groups reinforces the notion that these types of orthopaedic infections are often difficult to treat in all populations. Treatment of orthopaedic infections in RIVDU patients remains a challenging problem. Factors related to the host play a key role because patients may be malnourished, be immunocompromised, and be less likely to comply with recommended treatment.

Emerging Viral and Bacterial Infections: Within an Era of Opioid Epidemic

iv drug use complications

People with active hepatitis C may have elevated liver function tests (LF Ts), fatigue, and jaundice, and active disease can result in cirrhosis, liver cancer, and ultimately liver failure, all of which can be fatal. The hepatitis C virus can be cleared from the body with medication,  and over time, the liver may be able to regenerate itself. Hepatitis C is a serious https://ecosoberhouse.com/ health risk for people who inject drugs, many of whom have been exposed to the virus at  some point in their  lives. Those who regularly inject drugs are at a higher risk of developing an infection at the injection site. Septic arthritis is a painful infection that can cause extreme discomfort and limit the mobility of the infected joint and surrounding area.

  • Short-course intravenous or oral antibiotic regimens may be considered in some uncomplicated cases.69 Persons with severe valvular regurgitation from infectious endocarditis should be referred for valve replacement.
  • Low-molecular-weight heparin is an excellent antithrombotic drug that does not need to be monitored when used correctly.
  • General symptoms of early HIV infection (soon after the point of transmission) may include a low-grade fever and fatigue.
  • The diagnosis and management of our patient posed particular challenges due to concurrent sinusitis, which appeared more severe on the left side of the face based on CT imaging, while the EJV thrombophlebitis, myositis, and parotitis affected the right side of the face.
  • Use of hallucinogens can produce different signs and symptoms, depending on the drug.

IV Drug Use Can Destroy Your Veins

Intravenous Drug Use–Related Complications of the Hand and Upper Extremity

iv drug use complications

Leave a Comment

Your email address will not be published. Required fields are marked *